Controlling Microbial Growth In The Body: Antimicrobial Drugs (2/2) Question Preview (ID: 50002)


This Is Review Of The Second Half Of Chapter 10 For BIO113. There Are 15 Questions Total. TEACHERS: click here for quick copy question ID numbers.

When someone is said to have a drug allergy, what are they actually allergic to?
a) The drug itself
b) A breakdown product of the drug
c) The drug itself or a breakdown product of the drug
d) The largest biological component of the drug

Which concept uses a high concentration(s) of drug for long enough time to kill all sensitive cells and inhibit others long enough for the immune system to destroy?
a) Antimicrobial resistance
b) Inhibitory resistance
c) Microbiota resistance
d) Retarding resistance

Which of the following is NOT a mechanism of resistance?
a) Deactivation of drug pumps
b) Change in drug binding site
c) Decreased permiability
d) Use of alternative metabolic pathway

Antimicrobial resistance is...
a) Intrinsic
b) Acquired
c) Can be either intrinsic or aquired
d) Neither instrinsic or acquired

Which of the following defines an adaptive response in which microbes begin to tolerate an amount of drug that would ordinarily be inhibitory?
a) Allergy
b) Toxicity
c) Drug resistance
d) Drug superiority

How do allergies work?
a) When a reaction(s) occurs depends on the overall concentration of the drug or breakdown product
b) You experience a reaction(s) on first exposure and also on subsequent exposures
c) You are sensitized on first exposure, and then experience a reaction(s) on subsequent exposures
d) A reaction(s) occur spontaneously

When do superinfections occur?
a) When there is an overgrowth of normal flora
b) When there is a secondary infection
c) When an allergic reaction is accompanied by an infection
d) When an infection causes toxicity

Which drug is most commonly used for mycobacterial infections?
a) Ciprofloxacin
b) Rifampin
c) Fluconazole
d) Clotrimazole

Which of the following is NOT a major mode of action of antivirals?
a) Preventing the maturation of viral particles
b) Blocking transcription and translation of viral molecules
c) Barring penetration of virus into the host cell
d) Increasing membrane permiability

Ciprofloxacin is an example of which class of drugs (broad spectrum and very potent)?
a) Fluoroquinolones
b) Sulfonamides
c) Polymyxins
d) Polyenes

Which class of drug is usually given in combination with sulfolamides?
a) Polymyxins
b) Polyenes
c) Azoles
d) Trimethoprim

Polymyxins are ________ spectrum, while sulfonamides are ________ spectrum.
a) Broad, narrow
b) Narrow, broad
c) Narrow, narrow
d) Broad, broad

Inhibition of metabolic pathways is based on what?
a) Noncompetitive inhibition
b) Neither noncompetitive nor competitive inhibition
c) Competitive inhibition
d) Both noncompetitive and competitive inhibition

Which of the following drugs does NOT bind to fungal membranes and affect permeability?
a) Ergosterol
b) Fluconazole
c) Amphotericin B
d) Nystatin

Which of the following drug classes is especially toxic to kidneys?
a) Polymyxins
b) Polyenes
c) Azoles
d) Sulfonamides

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