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Controlling Microbial Growth In The Body: Antimicrobial Drugs (2/2)
Test Description: This is review of the second half of Chapter 10 for BIO113. There are 15 questions total.
Instructions: Answer all questions to get your test result.
1) Which of the following drugs does NOT bind to fungal membranes and affect permeability?
A
Nystatin
B
Ergosterol
C
Amphotericin B
D
Fluconazole
2) Which of the following drug classes is especially toxic to kidneys?
A
Polymyxins
B
Sulfonamides
C
Polyenes
D
Azoles
3) Inhibition of metabolic pathways is based on what?
A
Noncompetitive inhibition
B
Neither noncompetitive nor competitive inhibition
C
Both noncompetitive and competitive inhibition
D
Competitive inhibition
4) Polymyxins are ________ spectrum, while sulfonamides are ________ spectrum.
A
Broad, narrow
B
Narrow, broad
C
Narrow, narrow
D
Broad, broad
5) Which class of drug is usually given in combination with sulfolamides?
A
Azoles
B
Polymyxins
C
Trimethoprim
D
Polyenes
6) Ciprofloxacin is an example of which class of drugs (broad spectrum and very potent)?
A
Polyenes
B
Sulfonamides
C
Fluoroquinolones
D
Polymyxins
7) Which drug is most commonly used for mycobacterial infections?
A
Clotrimazole
B
Ciprofloxacin
C
Rifampin
D
Fluconazole
8) Which of the following is NOT a major mode of action of antivirals?
A
Blocking transcription and translation of viral molecules
B
Barring penetration of virus into the host cell
C
Preventing the maturation of viral particles
D
Increasing membrane permiability
9) When do superinfections occur?
A
When an allergic reaction is accompanied by an infection
B
When there is an overgrowth of normal flora
C
When an infection causes toxicity
D
When there is a secondary infection
10) How do allergies work?
A
You experience a reaction(s) on first exposure and also on subsequent exposures
B
You are sensitized on first exposure, and then experience a reaction(s) on subsequent exposures
C
A reaction(s) occur spontaneously
D
When a reaction(s) occurs depends on the overall concentration of the drug or breakdown product
11) Which of the following defines an adaptive response in which microbes begin to tolerate an amount of drug that would ordinarily be inhibitory?
A
Drug superiority
B
Drug resistance
C
Toxicity
D
Allergy
12) Antimicrobial resistance is...
A
Can be either intrinsic or aquired
B
Intrinsic
C
Neither instrinsic or acquired
D
Acquired
13) Which concept uses a high concentration(s) of drug for long enough time to kill all sensitive cells and inhibit others long enough for the immune system to destroy?
A
Microbiota resistance
B
Retarding resistance
C
Inhibitory resistance
D
Antimicrobial resistance
14) Which of the following is NOT a mechanism of resistance?
A
Change in drug binding site
B
Decreased permiability
C
Use of alternative metabolic pathway
D
Deactivation of drug pumps
15) When someone is said to have a drug allergy, what are they actually allergic to?
A
The drug itself or a breakdown product of the drug
B
The largest biological component of the drug
C
The drug itself
D
A breakdown product of the drug
*select an answer for all questions
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