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Cell Divsion II
Test Description: AP Biology review of cell division
Instructions: Answer all questions to get your test result.
1) Movement of the chromosomes during anaphase would be most affected by a drug that
A
prevents shortening of microtubules
B
prevents attachment of the microtubules to the kinetochore
C
reduces cyclin concentrations
D
prevents shortening of microtubules
2) Which of the following is a function of those spindle microtubules that do not attach to kinetochores?
A
maintaining an appropriate spacing among the moving chromosomes
B
producing a cleavage furrow when telophase is complete
C
providing the ATP needed by the fibers attached to kinetochores
D
maintaining the region of overlap of fibers in the cell's center
3) What causes the decrease in the amount of cyclin at a specific point in the cell cycle?
A
the changing ratio of cytoplasm to genome
B
the cascade of increased production once its protein is phosphorylated by Cdk
C
its destruction by a process initiated by the activity of its complex with a cyclin
D
an increase in production once the restriction point is passed
4) Which of the following is released by platelets in the vicinity of an injury?
A
cyclin
B
PDGF
C
protein kinase
D
MPF
5) Which of the following is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?
A
protein kinase
B
Cdk
C
cyclin
D
PDGF
6) A mutation results in a cell that no longer produces a normal protein kinase for the M phase checkpoint. Which of the following would likely be the immediate result of this mutation?
A
The cell would never enter prophase
B
The cell would never leave metaphase.
C
The cell would undergo normal mitosis, but fail to enter the next G1 phase.
D
The cell would prematurely enter anaphase.
7) Which of the following is true concerning cancer cells?
A
They do not exhibit density-dependent inhibition when growing in culture.
B
They are not subject to cell cycle controls.
C
When they stop dividing, they do so at random points in the cell cycle.
D
all
8) A particular cell has half as much DNA as some other cells in a mitotically active tissue. The cell in question is most likely in
A
G2
B
Metaphase
C
Prophase
D
G1
9) One difference between cancer cells and normal cells is that cancer cells
A
continue to divide even when they are tightly packed together.
B
are arrested at the S phase of the cell cycle
C
are unable to synthesize DNA.
D
are always in the M phase of the cell cycle.
10) The drug cytochalasin B blocks the function of actin. Which of the following aspects of the cell cycle would be most disrupted by cytochalasin B?
A
spindle formation
B
cleavage furrow formation
C
DNA synthesis
D
spindle attachment to kinetochores
*select an answer for all questions
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