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Antigen Recognition By T Cells
Test Description: Outline the process of antigen recognition by T cells
Instructions: Answer all questions to get your test result.
1) T cells will only recognise...
A
Peptides
B
Enzymes
C
Proteins
D
Antibodies
2) T cells recognise antigens using...
A
Antigen presenting cells
B
Proteins
C
B cells
D
Surface-bound antibodies
3) T regulatory (Treg) cells...
A
Regulate the T cell response once it has been initiated
B
Are part of the IL-2 complex
C
All of the above
D
Rely on Foxp3 to carry out function
4) T cells undergo training in the...
A
Bone marrow
B
Secondary lymphoid tissue
C
Liver
D
Thymus
5) The TCR complex in T helper cells incorporates...
A
An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
B
An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD4
C
An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
D
An MHC class II molecule, a peptide, TCR alpha and beta chains, CD3 and CD4
6) The TCR in cytotoxic T lymphocytes incorporates...
A
An MHC class II molecule, a peptide, TCR alpha and beta chains, CD3 and CD4
B
An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
C
An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD4
D
An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
7) T helper cells activate...
A
Macrophages and NK cells by IFN-gamma and CTLs and B cells by IL-2
B
Macrophages, NK cells, CTLs and B cells by IL-2
C
Macrophages and NK cells by IL-2 and CTLs and B cells by IFN-gamma
D
Macrophages, NK cells, CTLs and B cells by IFN-gamma
8) The only cells that can present exogenous antigens to both class I and class II MHCs are...
A
Macrophages
B
T cells
C
Dedritic cells
D
B cells
9) The MAIN reason for differences in individual\'s T cell receptor repetoire is...
A
MHC positive and negative selection
B
Germline differences
C
Recombination
D
PAMP activation
10) The role of positive and negative selection is to...
A
Facilitate recombination of DNA
B
Ensure there is sufficient MHC diversity
C
Ensure the entire population of cells are capable of distinguishing self from non-self
D
Apoptose cells that recognise self-MHC molecules
*select an answer for all questions
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