Antigen Recognition By T Cells Question Preview (ID: 5894)


Outline The Process Of Antigen Recognition By T Cells. TEACHERS: click here for quick copy question ID numbers.

T cells will only recognise...
a) Proteins
b) Antibodies
c) Enzymes
d) Peptides

T cells recognise antigens using...
a) Surface-bound antibodies
b) B cells
c) Proteins
d) Antigen presenting cells

T regulatory (Treg) cells...
a) Regulate the T cell response once it has been initiated
b) All of the above
c) Rely on Foxp3 to carry out function
d) Are part of the IL-2 complex

T cells undergo training in the...
a) Bone marrow
b) Secondary lymphoid tissue
c) Thymus
d) Liver

The TCR complex in T helper cells incorporates...
a) An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
b) An MHC class II molecule, a peptide, TCR alpha and beta chains, CD3 and CD4
c) An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
d) An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD4

The TCR in cytotoxic T lymphocytes incorporates...
a) An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
b) An MHC class II molecule, a peptide, TCR alpha and beta chains, CD3 and CD4
c) An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD8
d) An MHC class I molecule, a peptide, TCR alpha and beta chains, CD3 and CD4

T helper cells activate...
a) Macrophages, NK cells, CTLs and B cells by IL-2
b) Macrophages and NK cells by IL-2 and CTLs and B cells by IFN-gamma
c) Macrophages and NK cells by IFN-gamma and CTLs and B cells by IL-2
d) Macrophages, NK cells, CTLs and B cells by IFN-gamma

The only cells that can present exogenous antigens to both class I and class II MHCs are...
a) T cells
b) Dedritic cells
c) Macrophages
d) B cells

The MAIN reason for differences in individual\'s T cell receptor repetoire is...
a) Germline differences
b) PAMP activation
c) MHC positive and negative selection
d) Recombination

The role of positive and negative selection is to...
a) Facilitate recombination of DNA
b) Apoptose cells that recognise self-MHC molecules
c) Ensure there is sufficient MHC diversity
d) Ensure the entire population of cells are capable of distinguishing self from non-self

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