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Controlling Microbial Growth In The Body: Antimicrobial Drugs (2/2)
Test Description: This is review of the second half of Chapter 10 for BIO113. There are 15 questions total.
Instructions: Answer all questions to get your test result.
1) Which of the following drugs does NOT bind to fungal membranes and affect permeability?
A
Ergosterol
B
Amphotericin B
C
Fluconazole
D
Nystatin
2) Which of the following drug classes is especially toxic to kidneys?
A
Polymyxins
B
Azoles
C
Polyenes
D
Sulfonamides
3) Inhibition of metabolic pathways is based on what?
A
Competitive inhibition
B
Noncompetitive inhibition
C
Both noncompetitive and competitive inhibition
D
Neither noncompetitive nor competitive inhibition
4) Polymyxins are ________ spectrum, while sulfonamides are ________ spectrum.
A
Narrow, broad
B
Narrow, narrow
C
Broad, narrow
D
Broad, broad
5) Which class of drug is usually given in combination with sulfolamides?
A
Trimethoprim
B
Polymyxins
C
Polyenes
D
Azoles
6) Ciprofloxacin is an example of which class of drugs (broad spectrum and very potent)?
A
Polyenes
B
Sulfonamides
C
Fluoroquinolones
D
Polymyxins
7) Which drug is most commonly used for mycobacterial infections?
A
Clotrimazole
B
Fluconazole
C
Rifampin
D
Ciprofloxacin
8) Which of the following is NOT a major mode of action of antivirals?
A
Preventing the maturation of viral particles
B
Blocking transcription and translation of viral molecules
C
Increasing membrane permiability
D
Barring penetration of virus into the host cell
9) When do superinfections occur?
A
When an infection causes toxicity
B
When an allergic reaction is accompanied by an infection
C
When there is a secondary infection
D
When there is an overgrowth of normal flora
10) How do allergies work?
A
You experience a reaction(s) on first exposure and also on subsequent exposures
B
A reaction(s) occur spontaneously
C
When a reaction(s) occurs depends on the overall concentration of the drug or breakdown product
D
You are sensitized on first exposure, and then experience a reaction(s) on subsequent exposures
11) Which of the following defines an adaptive response in which microbes begin to tolerate an amount of drug that would ordinarily be inhibitory?
A
Allergy
B
Drug resistance
C
Drug superiority
D
Toxicity
12) Antimicrobial resistance is...
A
Intrinsic
B
Acquired
C
Can be either intrinsic or aquired
D
Neither instrinsic or acquired
13) Which concept uses a high concentration(s) of drug for long enough time to kill all sensitive cells and inhibit others long enough for the immune system to destroy?
A
Antimicrobial resistance
B
Microbiota resistance
C
Inhibitory resistance
D
Retarding resistance
14) Which of the following is NOT a mechanism of resistance?
A
Decreased permiability
B
Change in drug binding site
C
Use of alternative metabolic pathway
D
Deactivation of drug pumps
15) When someone is said to have a drug allergy, what are they actually allergic to?
A
The drug itself or a breakdown product of the drug
B
A breakdown product of the drug
C
The drug itself
D
The largest biological component of the drug
*select an answer for all questions
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